The algorithm for pathologic GERD
The Milan score is a validated high resolution manometry screening tool that helps physicians to determine the risk of pathologic GERD. It includes four variables: EGJ type, Ineffective esophageal motility (IEM), EGJ contractile integral (EGJ-CI) and the response to the straight leg raise maneuver (SLR). The sum of each parameter generates the Milan Score and a risk rate for an acid exposure time (AET) >6% at the pH-study.
The Milan Score estimates the chance of a positive pH-study (acid exposure time>6%) combining four high resolution manometry parameters. The risk is estimated based upon informations gathered prospectively in two studies:
For a more comprehensive understanding of the inclusion and exclusion criteria and the study’s methodology, we strongly encourage a thorough review of the referenced documents. It is important to be aware that the risk percentage generated by the Milan Score is an estimation and does not constitute a guarantee of specific outcomes. It should be noted that a positive pH-study result may be observed even when the associated risk is low.
The purpose of this information is not to supplant the necessity for further diagnostic tests but to augment the diagnostic capabilities of High Resolution Manometry in cases of suspected GERD. The Authors are not responsible for medical decisions that may be made based on the risk calculator estimates.
